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Journal: International Journal of Pharmaceutics: X
Article Title: Co-assembling de novo designed peptide with high-payload drug protein for noninvasive treatment of corneal neovascularization
doi: 10.1016/j.ijpx.2025.100410
Figure Lengend Snippet: (a) Schematic illustration of the PZA synthesis. (b) The hydrodynamic size distribution of PZA and PZA@Beva, tested by DLS. (c-d) The TEM images of PZA and PZA@Beva. (e) UV–vis absorbance of free FITC-Beva and PZA@FITC-Beva. In 500 μL reaction system, with the molar ratio of Zn(NO 3 ) 2 to (RHC) 3 at 1:2 and the concentration of (RHC) 3 at 4 mg/mL, the dependence of (f) EE% and (g) LC% on the concentration of Beva during the generation of PZA@Beva. The PZA@Beva particles in b-e were generated under a 500 uL system containing 1 mg Beva /mL and 2 mg (RHC) 3 , with the molar ratio of Zn(NO 3 ) 2 to (RHC) 3 at 1:2. The scale bar in (c) and (d) is 200 nm. Means (±S. E.) of n = 3 (at least) independent experiments.
Article Snippet: The size, polymer dispersity index (PDI) and zeta potential of PZA and PZA@Beva were measured using
Techniques: Concentration Assay, Generated